The following drug groups are to be discontinued prior to thallium persantin testing: * Theophyllines (24 Hrs prior to test) * Nitrates (to be ceased on the day of the test)
The ß-BLOCKERS These drugs work by decreasing myocardial contractility, decreasing heart rate and reducing arterial blood pressure. They are discontinued to allow the patient to reach a maximum heart rate during the stress test.
Drug name Generic name Alprenolol Aptinª Betacardª Atenolol Notemª Tenorminª Labetalol Presalolª Trandateª Metaprolol Betacaraª Betalocª Lopressorª Minaxª Oxprenolol Captolª Corbetonª Trasicorª Pindolol Barblocª Viskinª Practolol Eraldinª Propanolol Cardinolª Deralinª Inderalª Prololª Sotolol Sotocorª Timolol Blocadrenª
The CALCIUM ANTAGONISTS
Calcium antagonists block the entry of calcium into cardiac and vascular smooth muscle cells. This causes a decrease in the heart rate and force of myocardial contraction. They are discontinued 24 hours prior to the test as their additional vasodilatory properties may camouflage areas of "at risk" myocardium.
Diltiazem Cardizemª Vasocardolª Felodipine Agonª Plendilª Ca2+- channel blockers (cont.). Nifedipine Adalatª Anpineª Normodipine Perhexiline Pexidª Verapimil Ampexª Cordiloxª Isoptinª Veradilª Veracapsª
The NITRATES Organic nitrates are the most common medications employed for the treatment of angina pectoris. They are short acting vasodilators which act by relaxing vascular smooth muscle. They are discontinued on the day of the test as their use may cause areas of "at risk" myocardium to appear normal.
Glyceryl trinitrate Anginineª Nitrobidª Nitrodiscª Nitrolingual sprayª Transiderm nitroª Isosorbide dinitrate Isotrateª Isosorbide mononitrate Imdurª Isosorbide nitrate Isordilª Pentaerythritol Peritrateª
The THEOPHYLLINES Aminophylline Cardophyllineª Somophyllineª Choline theophyllinate Brondeconª Choledylª Theophylline Austinª Elixophyllineª Nuelinª Slo-bidª Theodurª
CAPTOPRIL RENAL DRUG LIST
ACE inhibitors should be discontinued for three days prior to commencement of captopril renal scans. .Angiotensin Converting Enzyme (ACE) is required to convert angiotensin(I) to angiotensin(II). Angiotensin(II) is a potent vasoconstrictor. Therefore, inhibiting the release of ACE interrupts the renin-angiotensin(I)-angiotensin(II) pathway with the net result being a drop in blood pressure.
The ACE-INHIBITORS
Chemical name Generic name Captopril Capotenª Enalapril Ampraceª Compraceª Renitecª Fosinopril Monoprilª Lisinopril Prinivilª Perindopril Coversylª Quinapril Accuprilª Asigª Ramipril Ramaceª Tritacª